Most people take their medications as recommended by their doctors. However, for some, medications can become less effective when used together. Sometimes, the effects can be so strange that your doctor may advise you to try a different combination. While it’s important to adhere to any regimen your doctor prescribes for you, it’s also vital that you understand the unintended consequences of combining medications.

When Should You Avoid Combining Medications?

If you’re already taking one of the medications mentioned below, you should try to avoid combining them. Sometimes, the effects of combining medications can be unpredictable, especially since scientists don’t fully understand all of the interactions between the drugs. According to the experts at Drugs.com, there’s some evidence suggesting that when used together, these medications can increase the risk of death. If this is a concern for you, discuss it with your doctor before you start taking the combination.

Which Drugs Should You Avoid Combining?

Experts at Drugs.com warn against combining the following medications:

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