Sildenafil citrate (Viagra) and tadalafil (Levitra) are both FDA-approved medications for erectile dysfunction (impotence). Together, these two medications are commonly known as the silderafil combination pill. Since both medications work in a similar manner, combining them is a popular option for people looking to save money while taking care of their sexual health. Unfortunately, not all combination pills are created equal, and the effects of some combination products have been known to be less than desirable. Furthermore, many doctors and pharmacies prohibit the combined use of sildenefil and tadalafil due to potential health risks. Before taking any kind of medication, including a combination product, it is imperative that you consult with your doctor or healthcare provider. There are several potential side effects that may occur when taking Viagra and/or Levitra. Some people have reported a headache, while others have complained of facial flushing, indigestion, diarrhea, and heartburn. As a general rule, older adults, people with prostates, and those who suffer from heart disease should not take these medications. Taking sildenafil and tadalafil does not pose any risk to your health, but it’s still not recommended for people with certain medical conditions.
Why Take Both Drugs If You’re Already On The Other One?
If you’re already taking a medication for erectile dysfunction, there is no reason to also try for a placebo effect by taking a different medication for the same condition. The problem is that some men may be under the impression that taking two medications will help them achieve a greater effect than taking one. However, this is not necessarily the case. For some men, taking a combination of sildenafil and tadalafil may actually have a less beneficial effect than taking sildenafil alone. Why? Because tadalafil inhibits the enzyme CYP3A4, which aids in the breakdown of sildenafil. As a result, the amount of available sildenafil will be greater, and thus, the effect may be greater than if you took just one of the medications. This issue can be particularly pronounced in people taking more than one ED medication. In some cases, the CYP3A4 inhibitor tadalafil has been shown to diminish the therapeutic effect of sildenafil (Viagra) by more than 50% in people with erectile dysfunction. What’s more is that in clinical trials, some men taking tadalafil and sildenafil actually reported a worse erectile response than men taking sildenafil alone.
Risks Of Combining These Two Medications
As mentioned above, combining sildenafil with tadalafil can diminish the beneficial effect of sildenafil by up to 50%. While this might seem like a good idea at first, there are some significant risks to consider. First off, if you combine these two medications and experience a diminution of effect, there is no way of knowing how long the effect will last. You could potentially suffer from a severe, lasting erection for several hours or even days. This could cause significant damage to your penis and/or testicles, especially if you have any kind of trauma or injury during sex play. Another major risk is that sildenafil and tadalafil have a known interaction when taken together. In some cases, people taking sildenafil and tadalafil have experienced a sudden drop in blood pressure and even collapsed while having sex. In more severe cases, people taking these medications have suffered from heart attacks and even deaths. Unfortunately, this issue is not very well-understood and there does not seem to be a clear answer as to why this happens. Some hypothesize that an interaction occurs between the nitric oxide (NO) pathways of sildenafil and tadalafil, which results in the lowering of blood pressure. Still, others believe that an interaction occurs between the PDE5 inhibitors (sildenafil and tadalafil) and the alpha-adrenergic receptors (specifically, the alpha-1 receptor) in the blood vessels of the penis. In most cases, the combination of these two medications is not recommended, and this is because there is no guarantee that the effect will last for the entire duration of sexual activity. Due to these risks, some doctors and pharmacists will not prescribe or dispense sildenafil and tadalafil together, even though they’re FDA-approved for use together. As a general rule, people who suffer from cardiovascular disease, asthma, and hypothyroidism should not take sildenafil and tadalafil, as they may have negative feedback effects on these systems.
Fortunately, there is an alternative option available for men with erectile dysfunction. If you’re already taking a medication for erectile dysfunction and you want to try a different drug for the same condition, there is a wide variety of options available. Some of the most popular alternative medications include vardenafil (Levitra), aviptap (terazosin), and udenafil (ST-25). As mentioned above, combining sildenafil with tadalafil can diminish the beneficial effect of sildenafil by up to 50%. In most cases, this effect will only last for a few hours or a day before you need to take another dose. In comparison, many of the above-mentioned alternatives have a much longer half-life and may be able to maintain an erection for several hours or days. In some cases, the effect of the alternative medications may be even better than that of sildenafil and tadalafil because they don’t have the same interaction as the latter two medications and thus there is no chance of an adverse effect. In some instances, people taking vardenafil have had an improvement in erectile function of more than 60% and in others, the effect has been more than 80%. Even though most men will experience some level of side effect when taking a medication for erectile dysfunction, the alternative choices available offer significant advantages and should be considered before opting for a combination pill cocktail. Of course, if these alternatives are not available where you live, then a combination pill could still be a viable option for you.
If you’re interested in trying a different drug for erectile dysfunction, then it might be a good idea to consult with a reputable doctor or pharmacist. They will be able to advise you of the risks and benefits of each medication and help you choose the right treatment for your specific circumstances. In most cases, this is the best option because most people will experience some level of side effect when taking a medication for erectile dysfunction. Still, in some instances, the side effects may be less, and in others, more pronounced than those of the standard treatment. Ultimately, you and your doctor will have to decide together whether or not this is a safe and viable option for you to consider.