A new drug has recently received FDA approval called SPLIT VIAGRA. This new drug is a combination of sildenafil, an oral solution, and avanafil, an inhalation solution. It was approved for the treatment of erectile dysfunction (commonly known as “Viagra”). However, does this new medicine offer any advantages to patients over the standard ED treatment option, Viagra? We will compare the two and see which one is right for you.
Characteristics And How Does It Work
Let’s start by comparing the two drugs: Viagra and Split Viagra. Viagra was first approved by the FDA in April 1998 and was designed to treat erectile dysfunction in men. It is a PDE5 inhibitor, which helps relax blood vessels in the penis and allows more blood to flow into it when a man becomes sexually stimulated. This improves the penis’ ability to become erect and boosts his self-esteem.
In 2016, Splital VIAGRA was approved by the FDA as a treatment for erectile dysfunction. It is a combination of sildenafil and avanafil, two medicines that work together to treat erectile dysfunction. It is important to note that both compounds in Splital VIAGRA inhibit PDE5, the enzyme that helps break down cGMP, but they do this in a different way. Sildenafil inhibits the enzyme directly while avanafil inhibits it indirectly by blocking an enzyme called PDE6, which metabolizes cGMP. Together, these two compounds increase the level of cGMP in the Penile Blood Vessels, which results in improved erections and sensitivity as well as increased sexual desire. This medicine is currently an option for patients who are unable to use Viagra because it inhibits the same enzyme (PDE5) and has a similar mechanism of action.
Advantages Of Taking Splital VIAGRA
Although Viagra and Split Viagra have similar mechanisms of action and were both designed to treat erectile dysfunction, there are several advantages to taking Splital VIAGRA instead of plain old Viagra. One advantage is that you do not need to take as much Splital VIAGRA compared to when you take Viagra. The standard adult dose of Splital VIAGRA is one hundred milligrams (mg) daily, while the standard adult dose of Viagra is fifty milligrams three times daily. The dose for children, however, is different and it is ten milligrams daily.
Another advantage is that you can take Splital VIAGRA with or without food. This is beneficial because sometimes men have trouble swallowing oral pills and it can also help improve the tolerability and effectiveness of the medicine. The absorption of Splital VIAGRA is also very high due to its PDE5 inhibitor chemical structure. This allows the drug to enter the bloodstream more quickly and effectively. While oral absorption is very high, the bioavailability (the percentage of the drug that is absorbed) is not as high. This sometimes leads to inconsistent or unpredictable results. But, since the drug does seem to work for many men, you can consider this a positive aspect.
Are There Any Disadvantages To Taking Splital VIAGRA?
While there are several advantages to taking Splital VIAGRA for erectile dysfunction treatment, it also has several disadvantages. First, like Viagra, it is an oral medication and this can make it more difficult to control your consumption of it or administer it to children, the elderly, or those with poor oral tolerability. Second, both medications, including Splital VIAGRA, cause blood pressure (BP) to rise, so they should not be taken by anyone who already takes medications for high blood pressure or suffers from coronary artery disease (CAD). Third, men with prostate cancer should not take this medication due to the anti-cancer effects of sildenafil and the unknown safety of avanafil in this population. Fourth, like Viagra, this medication can cause heart-related side effects, such as a prolonged QT interval (sometimes referred to as “torsades de pointes” or “TdP”). This is an abnormality in the heart’s electrical activity and can lead to chaotic and dangerous heart rhythms. Finally, some men have reported that taking Viagra or this drug combination can cause headaches, upset stomachs, and dizziness.
Key Differences Between Viagra And Split Viagra
Now that you know the similarities and the major differences between Viagra and Splital VIAGRA, you can get a clearer picture of which one is right for you. The most significant difference between Viagra and Split VIAGRA is the rate at which they work. As discussed previously, Viagra is a PDE5 inhibitor and this mainly affects how it works. In general, these types of medications increase the amount of cGMP in the body. The increased cGMP then has several downstream effects, one of which is to relax and dilate the blood vessels in the penis (more blood flows into it, which makes it harder and more comfortable for a man to become erect).
In contrast, Split VIAGRA is a combination of two different PDE5 inhibitors and this results in an overall greater effect. While the exact mechanism of action of this drug is not fully understood, it is believed that it increases the chances of an erection at least being somewhat satisfactory as well as increasing the chances of a man feeling sexually satisfied during intercourse. Because this combination of medications has a more pronounced effect than sildenafil alone, it may be a better option for some men who suffer from erectile dysfunction. It is also important to note that while your doctor may prescribe you one medication to treat your erectile dysfunction, he may also recommend that you try a different option, such as this combination of sildenafil and avanafil.