While we wait for the next big drug discovery to hit the market, we can find some relief in the form of effective pharmaceutical alternatives. One of these alternatives is Viagra, and although it was initially developed to treat elevated blood pressure, it has since been found to be effective in treating erectile dysfunction in otherwise healthy men. However, now that we’re coming off the peak of the pandemic, more men are turning to natural alternatives to Viagra, and specifically to citalis.
So which is better: Viagra or citalis? Let’s compare their chemical structures and the properties that make them effective when treating ED and BP in men.
Similar Physicochemical Properties
At first glance, Viagra and citalis may seem quite similar, and in fact, they are both classified as PDE5 inhibitors, which is an important pharmacokinetic class because it means they both act the same way in the body to inhibit the action of an enzyme, PDE5. PDE5 is responsible for breaking down cGMP, which stands for cyclic GMP, a naturally-occurring compound within the walls of smooth muscle cells. When broken down, the compound cGMP increases the relaxation of smooth muscle cells, which in turn increases blood flow throughout the body. This particular property makes PDE5 inhibitors attractive candidates for the treatment of ED and hypertension. Now let’s take a closer look at the similarities and differences between these two compounds.
Key Differences
There are several key differences between Viagra and citalis that you need to be aware of before deciding which one is better suited for your needs. The most significant difference is their chemical makeup. In addition to having similar chemical structures, Viagra and citalis also share several common compounds. Citalis, however, also contains two important compounds that are not found in Viagra:
- cis-3-Acetoxy-4-hydroxy-tetrahydrofuran-2-one
- (–)-N-methyl-3-(2-methyl-2H-1,2,3-benzothiadiazol-4-yl)-4-(4-chlorophenyl)-2-butanamide
- N-(3-Benzoyl-4-hydroxy-tetrahydrofuran-2-yl)-3-[(2-methyl-2H-1,2,3-benzothiadiazol-4-yl)]-2-butanamide
- 2-(3,4-Dihydroxy-phenyl)-3-methyl-2,4-thiazolidinedione
- 5-Amino-3-methylisoxazole-4-carboxamide
These compounds are shared between the two drugs, but they play distinct roles in the body. Viagra is a combination of compounds that work together to increase blood flow through the vascular system. This particular property makes it a better choice for the treatment of erectile dysfunction because it helps provide an effective alternative to men who cannot tolerate the side effects of nitrates, which are compounds typically used to treat angina and heart disease. Although men with serious heart diseases should not take Viagra, many do find it effective in treating their erectile dysfunction, so long as they do not also take nitrates at the same time. Citalis, on the other hand, is much more potent than Viagra and is thus better suited for men who need a stronger erection or who want to experience more intense orgasms. This drug is effective for both the treatment of ED and hypertension, but your doctor will need to adjust your dosage depending on which condition you are more likely to suffer from. In any case, both compounds have positive effects on the body that can be enjoyed by men who take them regularly.
Side Effects
Despite their effectiveness in treating ED and hypertension, neither drug is without its risks. Both compounds can cause various side effects, most notably headaches and flushing. These headaches and flushing are thought to be caused by nitrate compounds that are present in both drugs. It’s also worth noting that neither drug is suitable for use by women or children. In addition, since Viagra is a prescription drug, you need to be aware that you might experience some side effects from it, such as headaches, dizziness, and lightheadedness. Sometimes these side effects can be serious and even lead to death. There are also reports of sudden death in men who have taken Viagra, even in those who have no prior history of heart disease. While the link between Viagra and sudden death is not yet fully understood, it is thought to be caused by a condition known as ‘hypersensitivity reaction’. Men with this condition have an exaggerated response to compounds similar to cGMP, including compounds found in Viagra. It is therefore imperative that individuals with hypersensitivity problems who take Viagra come off it immediately if they experience any adverse effects. It’s also a good idea to consult your doctor before taking either of these compounds if you are already taking nitrates or aspirin, as these drugs can also cause interactions.
In summary, both Viagra and citalis are PDE5 inhibitors, and although they are both effective in the treatment of erectile dysfunction and hypertension, each one has its perks and quirks. If you’re wondering which one is better suited for your needs, it might be best to try both out and see how you feel after using each one. Some men might prefer one over the other for reasons I’ve described above, but for the most part, they are both great options for men who need help with their erectile dysfunction or hypertension, as long as they are used responsibly.